Opening windows of opportunities: Evidence for interventions to prevent or treat depression in pregnant women being associated with changes in offspring's developmental trajectories of psychopathology risk

Opening windows of opportunities: Evidence for interventions to prevent or treat depression in pregnant women being associated with changes in offspring's developmental trajectories of psychopathology risk

Forfattere
Goodman, S. H. Cullum, K. A. Dimidjian, S. River, L. M. Kim, C. Y.
Årstall
2018
Tidsskrift
Development and Psychopathology
Volum
30
Sider
1179-1196
Although animal models and correlational studies support a model of fetal programming as a mechanism in the transmission of risk for psychopathology from parents to children, the experimental studies that are required to empirically test the model with the human prenatal dyad are scarce. With a systematic review and meta-analysis of the literature, we critically examined the evidence regarding the neurobiological and behavioral changes in infants as a function of randomized clinical trials to prevent or reduce maternal depression during pregnancy, treating randomized clinical trials as experiments testing the fetal programming model. Based on 25 articles that met inclusion criteria, we found support for interventions designed to change maternal prenatal mood being associated with changes in offspring functioning, but with a very small effect size. Effect sizes ranged broadly, and were higher for younger children. The findings enhance understanding of putative mechanisms in the transmission of risk from women's prenatal depression to infants' vulnerabilities to, and early signs of, the development of psychopathology. We note limitations of the literature and suggest solutions to advance understanding of how preventing or treating depression in pregnant women might disrupt the transmission of risk to the infants.

Oversett med Google Translate
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Tiltaksnivå

Forebyggende og helsefremmende tiltak

Tidlig innsats

Behandling og hjelpetiltak

Tema

Foreldreferdigheter

Foreldrestress

Fødsels-/barselsdepresjon

Utvikling og livsmestring

Kognisjon (hukommelse, oppmerksomhet, eksekutive funksjoner)

Motorikk

Språk (reseptivt/ekspressivt)

Biologiske risikofaktorer, sykdommer og symptomer

Gravide (inkl. tenåringsmødre)

Tiltak

Psykologiske behandlingsmetoder

Foreldreveiledning/-terapi (feks COS, ICDP)

Kognitiv atferdsterapi, atferdsterapi og kognitiv terapi

Psykodynamisk/interpersonlig terapi

Psykoedukative tiltak (inkl. videobasert modellæring)

Psykososiale hjelpetiltak

Tiltak rettet mot gravide og barselkvinner

Alternativ behandling

Kosttilskudd og ernæring

Massasje

Aldersgruppe

Sped- og småbarn (0-2 år)

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