Metaanalyse over randomiserte, kontrollerte forsøk for pediatrisk tvangslidelse

Meta-analysis of randomized, controlled treatment trials for pediatric obsessive-compulsive disorder

Forfattere
Watson, H. J. Rees, C. S.
Årstall
2008
Tidsskrift
Journal of Child Psychology & Psychiatry & Allied Disciplines
Volum
49
Sider
489-98
OBJECTIVE: To conduct a meta-analysis on randomized, controlled treatment trials of pediatric obsessive-compulsive disorder (OCD). METHOD: Studies were included if they employed randomized, controlled methodology and treated young people (19 years or under) with OCD. A comprehensive literature search identified 13 RCTs containing 10 pharmacotherapy to control comparisons (N = 1016) and five cognitive-behavioral therapy (CBT) to control comparisons (N = 161). RESULTS: Random effects modeling yielded statistically significant pooled effect size (ES) estimates for pharmacotherapy (ES = .48, 95% CI = .36 to .61, p < .00001) and CBT (ES = 1.45, 95% CI = .68 to 2.22, p = .002). The results were robust to publication bias. CONCLUSIONS: This is the first meta-analysis of treatment RCTs for pediatric OCD. CBT and pharmacotherapy were the only treatments effective beyond control in alleviating OCD symptoms. CBT showed a greater ES than pharmacotherapy. Previous meta-analyses that included uncontrolled trials exaggerated the efficacy of both treatments.

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Tiltaksnivå

Behandling og hjelpetiltak

Tema

Psykiske vansker og lidelser

Angstproblematikk

Angst og engstelighet (inkl. både vansker og lidelse)

Tvangsforstyrrelser (OCD)

Tiltak

Psykologiske behandlingsmetoder

Kognitiv atferdsterapi, atferdsterapi og kognitiv terapi

Medikamentell behandling

Antidepressiva

Beroligende medisin

Aldersgruppe

Barn i skolealder (6-12 år)

Ungdom (13-18 år)

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