Psykofarmakologi og aggresjon: II. Metaanalyse av ikke-stimulerende medisinerings effekt på aggresjonsrelatert atferd hos unge med emosjonell forstyrrelse

Psychopharmacology and Aggression: II. A meta-analysis of nonstimulant medication effects on overt aggression-related behaviors in youth with SED

Forfattere
Connor, D. F. Boone, T. Steingard, R. J. Lopez, I. D. Melloni, R. H.
Årstall
2003
Tidsskrift
Journal of Emotional and Behavioral Disorders
Volum
11
Sider
157-168
Determined the effect size for nonstimulant medications on symptoms of overt aggression-related behaviors in referred children and adolescents with serious emotional and behavioral disturbances. A review of the literature between 1970 and 2001 revealed 33 studies meeting exclusion/inclusion criteria and yielding 37 independent effects for neuroleptic, atypical antipsychotic, mood stabilizer, antidepressant, and adrenergic agents on symptoms of overt aggression. Group 1 received medications for severely ill children (neuroleptics, mood stabilizers, etc...), while Group 2 received medications for less severely ill children (antidepressants). Overall weighted mean effect sizes were moderate to large for overt aggression within a heterogeneous group of psychiatric disorders. Moderators of effect size included drug group, study design, and the interaction between drug group and study design. The results support common clinical practice of including medications as part of a comprehensive psychoeducational treatment plan for some youth with maladaptive overt aggression within a variety of psychiatric disorders; however, not all referred youth respond to medication for overt aggression-related behavior, supporting the use of additional nonmedication interventions. (PsycINFO Database Record (c) 2012 APA, all rights reserved).

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Tiltaksnivå

Behandling og hjelpetiltak

Tema

Psykiske vansker og lidelser

Atferdsproblemer

Antisosial atferd (vold/aggresjon, ungdomskriminalitet)

Følelsesmessige problemer

Depresjon og nedstemthet (inkl. både vansker og lidelse)

Tiltak

Medikamentell behandling

Antidepressiva

Beroligende medisin

Antipsykotisk medisin

Aldersgruppe

Barn i skolealder (6-12 år)

Ungdom (13-18 år)

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