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New perspective on impact of folic acid supplementation during pregnancy on neurodevelopment/autism in the offspring children - A systematic review

New perspective on impact of folic acid supplementation during pregnancy on neurodevelopment/autism in the offspring children - A systematic review

Authors
Gao, Y. Sheng, C. Xie, R. H. Sun, W. Asztalos, E. Moddemann, D. Zwaigenbaum, L. Walker, M. Wen, S. W.
Year
2016
Journal
Plos One
Volume
11 (11) (no pagination)
Pages
Link to the publication
https://dx.doi.org/10.1371/journal.pone.0165626
It has been conclusively established that folic acid supplementation prior to and during early pregnancy (up to 12 weeks of gestation) can prevent neural tube defects (NTDs). We hypothesized that folate effects may extend from neuro-structural defects to alterations in neuro-behavioural and emotional skills including autism spectrum disorders (ASDs) and other developmental disorders. The objective of this review was to comprehensively evaluate evidence on the impact of folic acid on neurodevelopment other than NTDs. We conducted an online search of relevant literature compiled by the National Library of Medicine from Medline and EMBASE (searched on Dec 31, 2014:

Oversett med Google Translate
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Type of intervention

Treatment and Child Welfare Interventions

Topic

Mental Health Problems and Disorders

Autism Spectrum Disorder

Development and Life Coping Skills

Cognition

Intervention

Psychosocial Treatments

Interventions for Pregnant Women and Postpartum Women

Alternative Treatment

Nutritional Supplements and Nutrition

Age group

Infants and Toddlers (0-2 years)

Preschool Aged Children (3-5 years)

School Aged Children (6-12 years)

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