Effectiveness of non-pharmacological interventions on individuals with anorexia nervosa: A systematic review and meta-analysis

Effectiveness of non-pharmacological interventions on individuals with anorexia nervosa: A systematic review and meta-analysis

Authors
Gan, Javeil Ke En Wu, Vivien Xi Chow, Gigi Chan, Janice Kuang Yeung Klainin-Yobas, Piyanee
Year
2021
Journal
Patient Education and Counseling
Volume
Pages
No Pagination Specified
OBJECTIVE: This study aimed to synthesize the best available evidence regarding the effectiveness of non-pharmacological interventions on body mass index (BMI), body dissatisfaction, depression and anxiety among individuals with anorexia nervosa (AN). METHODS: Published studies in English were searched using seven databases (such as PubMed). Grey literature was searched using ProQuest and Scopus. Studies were screened, appraised and extracted by two independent reviewers. Meta-analysis was performed and standardized mean difference was used as an effect measure. Heterogeneity was determined by I2 statistics and Cochran chi2 test. Publication bias was appraised using funnel plots. Sensitivity and subgroup analyses were also conducted. RESULTS: Nineteen RCTs from eight different countries were included in this review. Behavioral family system therapy (BFST) was found to enhance BMI while conjoint family therapy (CFT) was more effective in ameliorating depression. Studies implementing combined family and individual therapy and those with longer therapeutic durations produced larger effect sizes. CONCLUSION: This review provided evidence to support BSFT, CFT and combined family and individual therapy for adolescents with AN. PRACTICAL IMPLICATIONS: Healthcare professionals may offer the two interventions to adolescents with AN in clinical settings. Future research may further investigate the effectiveness of BSFT and CFT on BMI and depression. (PsycInfo Database Record (c) 2021 APA, all rights reserved)

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Type of intervention

Treatment and Child Welfare Interventions

Topic

Mental Health Problems and Disorders

Eating Disorders

Intervention

Psychological Treatments

Family Therapy

Cognitive Behavioral Therapy, Behavioral Therapy and Cognitive Therapy

Psychodynamic/Interpersonal Therapy

Age group

Adolescents (13-18 years)

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